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Long-Term Effects of Undescended Testis on Male Fertility

March 17, 20255 min readUpdated Sep 23, 2026
Long-Term Effects of Undescended Testis on Male Fertility
Written byMITR Hospital Editorial Team
Published: Updated: Read time: 5 min read

Undescended testis, medically known as cryptorchidism, is a condition where one or both testicles fail to descend into the scrotum. This condition is commonly diagnosed in newborns and, if left untreated, can lead to complications, including damage to the testis, testicular torsion, infertility, or rarely malignancy. Studies suggest that approximately 3% of full-term male infants and up to 30% of preterm male infants are born with an undescended testis. Understanding the long-term effects of undescended testis on male fertility is crucial for timely diagnosis and treatment. At Mitr Hospital in Navi Mumbai, specialized treatment options are available to manage this condition effectively and prevent future fertility issues.

An undescended testis occurs when the testicle does not move into its proper position in the scrotum before birth. This condition can be unilateral (affecting one testis) or bilateral (affecting both testicles). If not corrected in early childhood, it may lead to testicular dysfunction, affecting sperm production and overall reproductive health.

How Does Undescended Testis Affect Male Fertility?

1. Impaired Sperm Production and risk of infertility

Testicles need to be in the scrotum, where the temperature is lower than the body’s core temperature. When a testis remains in the abdomen or groin, it is exposed to higher temperatures, which can negatively impact sperm production, leading to reduced sperm count and motility. Studies indicate that nearly 30-40% of men with a history of untreated bilateral undescended testis experience significant fertility issues.

2. Hormonal Imbalance

Testosterone, the primary male hormone, plays a crucial role in fertility. An undescended testis may not function properly, leading to hormonal imbalances that can impair sperm development and overall reproductive health.

3. Increased Risk of Testicular Cancer

Men with a history of undescended testis have a 2-8 times higher risk of developing testicular cancer compared to the general population. Furthermore, approximately 5-10% of testicular cancer cases have a history of undescended testis.

4. Testicular Atrophy

Prolonged exposure to abnormal temperatures can lead to testicular atrophy, where the testis shrinks and loses its ability to produce healthy sperm. This can lead to reduced testicular volume and diminished reproductive potential.

Treatment Options for Undescended Testis

1. Hormonal Therapy

In the past, hormone therapy using hCG (human chorionic gonadotropin) was used to stimulate testicular descent. However, research has shown that it may be harmful to the testis and is now considered obsolete.

2. Surgery (Orchiopexy)

Orchiopexy is a surgical procedure to reposition the undescended testis into the scrotum. This surgery is most effective when performed before the child turns one year old, significantly reducing the risk of infertility and testicular cancer.

3. Assisted Reproductive Techniques (ART)

For men who experience fertility issues due to untreated undescended testis, assisted reproductive techniques such as IVF (In Vitro Fertilization) and ICSI (Intracytoplasmic Sperm Injection) can help achieve parenthood.

Why Choose Mitr Hospital in Navi Mumbai for Treatment?

At Mitr Hospital in Navi Mumbai, expert pediatric urologists provide treatment for undescended testis. With state-of-the-art facilities and personalized care, patients receive appropriate surgical intervention at the right age to prevent long-term complications.

Conclusion

Undescended testis is a serious condition that can impact male fertility if left untreated. Early diagnosis and treatment at Mitr Hospital in Navi Mumbai can help prevent long-term complications. If your child has been diagnosed with cryptorchidism, consult a specialist today to explore the best treatment options.

FAQs About Long-Term Effects of Undescended Testis on Male Fertility

An undescended testis is a condition where one or both testicles do not move into the scrotum before birth.

It affects approximately 3% of full-term male infants and up to 30% of preterm male infants.

Yes, if left untreated, it can impair sperm production and increase the risk of fertility problems in adulthood.

The testicles need the cooler temperature of the scrotum for normal sperm production. A testis located in the abdomen or groin is exposed to higher temperatures, which can affect sperm development.

Yes, an undescended testis may not function normally, potentially affecting testosterone production and overall reproductive health.

Yes, men with a history of undescended testis have a higher risk of developing testicular cancer compared to the general population.

Testicular atrophy is the shrinking of the testis due to prolonged exposure to abnormal temperatures, which can reduce sperm production and fertility potential.

The standard treatment is orchiopexy, a surgical procedure that moves the testis into the scrotum.

Orchiopexy is most effective when performed before the child reaches one year of age, helping reduce future fertility and cancer risks.

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Yes, assisted reproductive techniques such as IVF and ICSI may help men with fertility challenges achieve parenthood. For evaluation and treatment, parents can consult the pediatric urology specialists at MITR Hospital.

 
 

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